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A series of integrated reactions with each step in the pathway controlled by a specific enzyme.

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1.  Irreversible step

   Reaction only proceeds in 1 direction

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2.  Reversible step

    Forward and backward reaction can occur

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3.  Alternative Routes

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high substrate/low product  drives the reaction in that particular direction.

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Forward reaction favoured

1. High A concentration

2. Low B concentration

 

 

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Backward reaction favoured

1. High B concentration

2. Low A concentration

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When a mutation becomes non functional (single gene mutation/inhibitor), 

Substrate immediately before reaction
Increases in concentration    

All products after reaction
Decrease in concentration

Any substrate not immediately before
Unaffected

 

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Larger substrate is converted into
a smaller product.

ATP released

 

Smaller substrate is converted into
a larger product.

ATP required.

 

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